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Xi Erick Lin, PhD

Xi Erick Lin, PhD

Primary Appointment:
Professor and Research Director, Department of Otolaryngology

Joint and Secondary Appointment:
Associate Professor, Department of Cell Biology

EDUCATION

PhD (1993): Neuroscience, University of Michigan

Postdoctoral Research Associate (1993-1994): Molecular Cardiology Laboratory, Department of Medicine, University of Chicago

Postdoctoral Research Associate (1994-1996): Auditory Physiology Lab, Northwestern University, Chicago

CURRENT AND FORMER APPOINTMENTS

Primary Appointment: Professor and Research Director, Department of Otolaryngology, Emory University School of Medicine

Joint and Secondary Appointment: Associate Professor, Department of Cell Biology, Emory University School of Medicine

2001-2003: Scientist II, Chief, Section on Neurobiology, Department of Cell and Molecular Biology, House Ear Institute, Los Angeles

2001-2003: Adjunct Assistant Professor, Department of Otolaryngology, University of Southern California, Los Angeles

1996-2001: Scientist I, Chief, Section on Neurobiology, Department of Cell and Molecular Biology, House Ear Institute, Los Angeles

EDITORSHIPS AND EDITORIAL BOARDS

Editorial Board, Chinese Journal of Audiology and Speech Pathology

Publications Committee, Journal of Association of Research Otolaryngology

Academic Editor, PLoS One

PROFESSIONAL MEMBERSHIPS

Association for Research in Otolaryngology

Society for Neuroscience

American Society of Human Genetics

RECENT PUBLICATIONS

Z. Gao Z, M.C. Kelly, D. Yu, H. Wu, X. Lin, F.L. Chi, P. Chen (2015). "Spatial and age-dependent hair cell generation in the postnatal mammalian utricle." Mol Neurobiol. 2015 Feb 10. PMID: 25666161.

X. Gao, S.S. Huang, Y.Y. Yuan, G.J. Wang, J.C. Xu, Y.B. Ji, M.Y. Han, F. Yu, D.Y. Kang, X. Lin and P. Dai (2015). "Targeted Gene Capture and Massively Parallel Sequencing Identify TMC1 as the Causative Gene in a Six-generation Chinese Family with Autosomal Dominant Hearing Loss." Am J Med Genet Part A 9999A:1–9. DOI: 10.1002/ajmg.a.37206.

Q. Chang, J.J. Wang, Q. Li, Y.J. Kim, B.F. Zhou, Y.F. Wang, H.W Li, X. Lin (2015). "Virally mediated Kcnq1 gene replacement therapy in the immature scala media restores hearing in a mouse model of human Jervell and Lange-Nielsen deafness syndrome." EMBO Molecular Medicine, 7, 1077-1086. DOI 10.15252/emmm. 201404929.

Y. Sun, J.T. Yu, X. Lin, W.X. Tang (2016). "Inhibition of cyclooxygenase-2 by NS398 attenuates noise-induced hearing loss in mice." Scientific Reports, 6: 22573. DOI: 10.1038/srep22573.

X.X. Zhou, S. Chen, L. Xie, Y.Z. Ji, X. Wu, W.W. Wang, Q. Yang, J.T. Yu, Y. Sun, X. Lin, W.J. Kong (2016). "Reduced Connexin26 in the mature cochlea increases susceptibility to noise-induced hearing loss in mice." Int. J. Mol. Sci. 17(115); doi:10.3390.

RESEARCH FOCUS

Dr. Lin studies the mechanisms of genetic deafness caused by mutations in connexin (GJB2 & GJB6 genes), pendrin (SLC26A4 gene), and other deafness genes. He is also investigating how membrane channels/receptors contribute to normal cochlear physiology and homeostasis.

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