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Steven L. Goudy, MD

Steven L. Goudy, MD

Associate Professor
Otolaryngology – Head & Neck Surgery

Director, Division of Pediatric Otolaryngology
Children's Healthcare of Atlanta

EDUCATION

BS: Centre College Danville, KY
MD: University of Louisville, Louisville, KY
Residency: University of Louisville
Pediatric Otolaryngology Fellowship: University of Iowa

LICENSES/CERTIFICATIONS

American Board of Otolaryngology – Head & Neck Surgery

FORMER APPOINTMENTS

Associate Professor of Otolaryngology, Vanderbilt University School of Medicine, 2012-2015
Assistant Professor of Otolaryngology, Vanderbilt University School of Medicine, 2005-2012

HONORS AND AWARDS

Communication Service Award, Bill Wilkerson Speech and Hearing Sciences, Vanderbilt University Medical Center, 2008
Patient Choice Award, American Registry Organization, 2008-2014
Best Doctors Award, Best Doctors Organization, 2010-2014
Best Pediatric Otolaryngology Award, 2013-2014
Otolaryngology-Head and Neck Surgery Honor Award, American Academy of Otolaryngology, 2010
Patient Safety Award, Vanderbilt University Medical Center, 2013
Resident Teaching Award, Vanderbilt University School of Medicine, 2014

CURRENT PROFESSIONAL MEMBERSHIPS

American College of Surgeons, Fellow
American Academy of Otolaryngology Head Neck Surgery: Humanitarian Committee; Chair, Resident Travel Grant Selection; Pediatric Otolaryngology Committee; CORE Grant Review Committee
American Cleft Palate Association: Chair, Organizational Alliance Committee; Co-Chair, Organizational Alliances Committee; Chair, Otolaryngology Section of Org All Com; Chair, Revitalization Task Force
American Academy of Pediatrics: Oral Health Section, Council on Quality Improvement
American Facial Plastic Reconstructive Society
American Society of Pediatric Otolaryngology: Fellowship Director Committee, Research and Grant Committee
Society of ENT Advances in Children

CONDITIONS TREATED INCLUDE

Cleft lip and palate
Micrognathia (mandible deficiency)
Velopharyngeal insufficiency
Vascular malformations
Tumors of the head and neck
Chronic ear conditions
Pediatric sleep apnea
Hearing loss

CLINICAL FOCUS

While I provide comprehensive and compassionate care to all of my patients, I have a particular interest in treating development and neoplastic concerns of the head and neck region. Such craniofacial development abnormalities as cleft lip and palate, Pierre Robin Sequence, and velopharyngeal insufficiency are also a strong focus of my practice. Multidisciplinary collaboration is an important mechanism in my treatment approach, an example being my participation in teams of diverse specialists that evaluate and treat patients with vascular and neonplastic tumors of the head and neck region.

RESEARCH FOCUS

Cleft and craniofacial disorders are my primary clinical and basic research interests. Even though the surgical repair of cleft lip and palate is highly effective, patients will continue to be faced with ongoing medical, dental, and surgical care. Surgical outcomes can be variable, and the patient's facial growth and development is primarily the result of their genetic composition. Therefore, much of my research focuses on the problems that can develop during the years that follow surgery. 

Underdevelopment of the upper jaw is one of the main sequelae of cleft palate repair and causes maxillary hypoplasia. To uncover why this happens, I have assembled a team of collaborators that includes Drs. Nick Willett (Emory Department of Orthopedics), Gregory Gibson (Center for Integrative Genomics, Georgia Institute of Technology), and Michael Davis (Coulter Department of Biomedical Engineering at Georgia Tech and Emory University), all of whom are experts in the fields of bone and vascular biology. Our goal is to determine how cell autonomous and non-cell autonomous Jagged1 signaling during maxillary development contributes to final maxillary formation. 

I worked closely with Dr. Joey Barnett of the Department of Pharmacology at Vanderbilt while I was there, and he will continue to be my senior advisor as I evaluate the integration of Jagged1 and TgfßR3 signaling during maxillary mesenchymal cell differentiation and ossification. 

With assistance from Drs. Scott Boden (Emory Department of Orthopedics), Roberto Pacifici (Emory Department of Medicine), and Bob Taylor (Emory Department of Medicine), I am examining how intramembranous ossification of the maxillary and palatine bones contributes to later maxillary morphology. Dr. Greg Gibson (Director of the Center for Integrative Genomics, Georgia Tech) will help plan, execute, and analyze the RNA-seq data to identify the targets of Jagged1 signaling. We have already published our observations involving the bony phenotype and our conclusion that Wnt1-Cre;Jagged1 F/F mice are a viable model of post-natal maxillary hypoplasia. Once we have a wider understanding of maxillary development, we plan on developing targeted therapies for future in vitro and in vivo correction of maxillary hypoplasia in the Jag1CKO mice

RECENT PUBLICATIONS

Leslie EJ, O'Sullivan J, Cunningham ML, Singh A, Goudy SL, Ababneh F, Alsubaie L, Ch'ng GS, van der Laar IM, M Hoogeboom AJ, Dunnwald M, Kapoor S, Jiramongkolchai P, Standley J, Manak JR, Murray JC, Dixon MJ. Expanding the genetic and phenotypic spectrum of popliteal pterygium disorders. Am J Med Genet A. 2015 Mar;167(3):545-52.

Hill CR, Jacobs BH, Brown CB, Barnett JV, Goudy SL. Type III transforming growth factor beta receptor regulates vascular and osteoblast development during palatogenesis. Dev Dyn. 2015 Feb;244(2):122-33. Epub 2014 Dec 1.

Penn EB Jr, Goudy SL. Pediatric inflammatory adenopathy. Otolaryngol Clin North Am. 2015 Feb;48(1):137-51.

Sullivan JM, Bao S, Goudy R, Konet H. Characteristics of turn signal use at intersections in baseline naturalistic driving. Accid Anal Prev. 2015 Jan;74:1-7.

Biggs LC, Goudy SL, Dunnwald M. Palatogenesis and cutaneous repair: A two-headed coin. Dev Dyn. 2014 Nov 5.

Jabbour N, Chinnadurai S, Wootten CT, Cofer SA, Goudy SL. The 70-degree telescope as a teaching tool for cleft palate repair and pharyngoplasty surgery. Int J Pediatr Otorhinolaryngol. 2014 Nov;78(11):1833-6.

Crockett DJ, Goudy SL. Cleft lip and palate. Facial Plast Surg Clin North Am. 2014 Nov;22(4):573-86.

Crockett DJ, Ahmed SR, Sowder DR, Wootten CT, Chinnadurai S, Goudy SL. Velopharyngeal dysfunction in children with Prader-Willi syndrome after adenotonsillectomy. Int J Pediatr Otorhinolaryngol. 2014 Oct;78(10):1731-4.

Crockett DJ, Goudy SL. Update on surgery for velopharyngeal dysfunction. Curr Opin Otolaryngol Head Neck Surg. 2014 Aug;22(4):267-75.

Wootten CT, Chinnadurai S, Goudy SL. Beyond adenotonsillectomy: outcomes of sleep endoscopy-directed treatments in pediatric obstructive sleep apnea. Int J Pediatr Otorhinolaryngol. 2014 Jul;78(7):1158-62.

Hill CR, Yuasa M, Schoenecker J, Goudy SL. Jagged1 is essential for osteoblast development during maxillary ossification. Bone. 2014 May;62:10-21.

Crockett DJ, Goudy SL, Chinnadurai S, Wootten CT. Obstructive sleep apnea syndrome in children with 22q11.2 deletion syndrome after operative intervention for velopharyngeal insufficiency. Front Pediatr. 2014 Aug 11;2:84.

Kuo CY, Wootten CT, Tylor DA, Werkhaven JA, Huffman KF, Goudy SL. Prevention of pressure ulcers after pediatric tracheotomy using a Mepilex Ag dressing. Laryngoscope. 2013 Dec;123(12):3201-5.

Goudy S, Angel P, Jacobs B, Hill C, Mainini V, Smith AL, Kousa YA, Caprioli R, Prince LS, Baldwin S, Schutte BC. Cell-autonomous and non-cell-autonomous roles for IRF6 during development of the tongue. PLoS One. 2013;8(2):e56270.

Chinnadurai S, Goudy S. Understanding velocardiofacial syndrome: How recent discoveries can help you improve your patient outcomes. Curr Opin Otolaryngol Head Neck Surg. 2012 Dec;20(6):502-6.

Humphreys R, Zheng W, Prince LS, Qu X, Brown C, Loomes K, Huppert SS, Baldwin S, Goudy S. Cranial neural crest ablation of Jagged1 recapitulates the craniofacial phenotype of Alagille syndrome patients. Hum Mol Genet. 2012 Mar 15;21(6):1374-83.

Wright CT, Goudy SL. Congenital laryngomalacia: Symptom duration and need for surgical intervention. Ann Otol Rhinol Laryngol. 2012 Jan;121(1):57-60.

Goudy S, Ingraham C, Canady J. Noncleft velopharyngeal insufficiency: etiology and need for surgical treatment. Int J Otolaryngol. 2012;2012:296073.

Tollefson TT, White D, Brookes J, Goudy S. Velopharyngeal insufficiency and cleft. Int J Otolaryngol. 2012;2012:864069. Epub 2012 Nov 8.

Goudy S, Ingraham C, Canady J. The occurrence of velopharyngeal insufficiency in Pierre Robin Sequence patients. Int J Pediatr Otorhinolaryngol. 2011 Oct;75(10):1252-4.

Moss JR, Cofer S, Hersey S, Goudy S, Werkhaven J, Swanson E, Mantle C, Stowell N, Byrne D, Wang L, Labadie R. Comparison of clonidine, local anesthetics, and placebo for pain reduction in pediatric tonsillectomy. Arch Otolaryngol Head Neck Surg. 2011 Jun;137(6):591-7.

Rorick NK, Kinoshita A, Weirather JL, Peyrard-Janvid M, de Lima RL, Dunnwald M, Shanske AL, Moretti-Ferreira D, Koillinen H, Kere J, Mansilla MA, Murray JC, Goudy SL, Schutte BC. Genomic strategy identifies a missense mutation in WD-repeat domain 65 (WDR65) in an individual with Van der Woude syndrome. Am J Med Genet A. 2011 Jun;155A(6):1314-21.

Mankarious LA, Goudy SL. Craniofacial and upper airway development. Paediatr Respir Rev. 2010 Dec;11(4):193-8. Epub 2010 Aug 7. Review.

Goudy S, Bauman N, Manaligod J, Smith RJ. Congenital laryngeal webs: Surgical course and outcomes. Ann Otol Rhinol Laryngol. 2010 Oct;119(10):704-6.

Goudy S, Law A, Sanchez G, Baldwin HS, Brown C. Tbx1 is necessary for palatal elongation and elevation. Mech Dev. 2010 May-Jun;127(5-6):292-300.

Schuman TA, Jacobs B, Walsh W, Goudy SL. Iatrogenic perinatal pharyngoesophageal injury: A disease of prematurity. Int J Pediatr Otorhinolaryngol. 2010 Apr;74(4):393-7.

Goudy S, Lott D, Burton R, Wheeler J, Canady J. Secondary alveolar bone grafting: outcomes, revisions, and new applications.Cleft Palate Craniofac J. 2009 Nov;46(6):610-2.

Marcus CL, Smith RJ, Mankarious LA, Arens R, Mitchell GS, Elluru RG, Forte V, Goudy S, Jabs EW, Kane AA, Katz E, Paydarfar D, Pereira K, Reeves RH, Richtsmeier JT, Ruiz RL, Thach BT, Tunkel DE, Whitsett JA, Wootton D, Blaisdell CJ. Developmental aspects of the upper airway: Report from an NHLBI Workshop, March 5-6, 2009. Proc Am Thorac Soc. 2009 Sep 15;6(6):513-20.

Wootten CT, Goudy SL, Rutter MJ, Willging JP, Cotton RT. Airway injury complicating excision of thyroglossal duct cysts. Int J Pediatr Otorhinolaryngol. 2009 Jun;73(6):797-801.

Huang X, Goudy SL, Ketova T, Litingtung Y, Chiang C. Gli3-deficient mice exhibit cleft palate associated with abnormal tongue development. Dev Dyn. 2008 Oct;237(10):3079-87.

Ingraham CR, Kinoshita A, Kondo S, Yang B, Sajan S, Trout KJ, Malik MI, Dunnwald M, Goudy SL, Lovett M, Murray JC, Schutte BC. Abnormal skin, limb and craniofacial morphogenesis in mice deficient for interferon regulatory factor 6 (Irf6). Nat Genet. 2006 Nov;38(11):1335-40.

Goudy S, Lott D, Canady J, Smith RJ. Conductive hearing loss and otopathology in cleft palate patients. Otolaryngol Head Neck Surg. 2006 Jun;134(6):946-8.

Lentsch EJ, Goudy S, Sosnowski J, Major S, Bumpous JM. Microvessel density in head and neck squamous cell carcinoma primary tumors and its correlation with clinical staging parameters. Laryngoscope. 2006 Mar;116(3):397-400.

Yang GS, Bishop WP, Smith BJ, Goudy SL, Sato Y, Bauman NM. Radiographic and endoscopic measurements of esophageal length in pediatric patients. Ann Otol Rhinol Laryngol. 2005 Aug;114(8):587-92.

Goudy SL, Flynn MB. Diagnostic accuracy of palpation-guided and image-guided fine-needle aspiration biopsy of the thyroid. Ear Nose Throat J. 2005 Jun;84(6):371-4. P

Harrell S, Evans B, Goudy S, Winstead W, Lentsch E, Koopman J, Wo JM. Design and implementation of an ambulatory pH monitoring protocol in patients with suspected laryngopharyngeal reflux. Laryngoscope. 2005 Jan;115(1):89-92.

Wo JM, Jabbar A, Winstead W, Goudy S, Cacchione R, Allen JW. Hypopharyngeal pH monitoring artifact in detection of laryngopharyngeal reflux. Dig Dis Sci. 2002 Nov;47(11):2579-85.

Goudy SL, Miller FB, Bumpous JM. Neck crepitance: evaluation and management of suspected upper aerodigestive tract injury.Laryngoscope. 2002 May;112(5):791-5.

Lentsch EJ, Goudy S, Ganzel TM, Goldman JL, Nissen AJ. Rate of persistent perforation after elective tympanostomy tube removal in pediatric patients. Int J Pediatr Otorhinolaryngol. 2000 Aug 31;54(2-3):143-8.

Handy TC, Hanzlick R, Shields LB, Reichard R, Goudy S. Hypernatremia and subdural hematoma in the pediatric age group: is there a causal relationship? J Forensic Sci. 1999 Nov;44(6):1114-8.

Qazzaz HM, Goudy SL, Valdes R Jr. Deglycosylated products of endogenous digoxin-like immunoreactive factor in mammalian tissue. J Biol Chem. 1996 Apr 12;271(15):8731-7.

Qazzaz HM, Goudy S, Miller JJ, Valdes R Jr. Treatment of human serum with sulfosalicylic acid structurally alters digoxin and endogenous digoxin-like immunoreactive factor. Ther Drug Monit. 1995 Feb;17(1):53-9.

Schutte BC, Saal HM, Goudy S, Leslie E. IRF6-Related Disorders. 2003 Oct 30 [updated 2014 Jul 03]. In: Pagon RA, Adam MP, Ardinger HH, Bird TD, Dolan CR, Fong CT, Smith RJH, Stephens K, editors. GeneReviews® [Internet]. Seattle (WA): University of Washington, Seattle; 1993-2014. 

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